Immersion Hypothermia: Effect of Glycine.
The intravenous administration of a 5% glycine solution caused a significant increase of 34.6 minutes in the time required to lower the rectal temperature of dogs from 38°C to 26°C. Total rewarming time was decreased by 34.3 minutes in the glycine treated group. The differences in cooling and rewarming rates between the treated and non-treated animals was due to the increased heat production observed in the dogs receiving glycine. The possible applicability of thermogenic agents in accidental hypothermia is discussed.

Thirty grams of glycine were administered orally to five volunteer, male subjects who were subsequently exposed nude to an environment of 10° C. Measurements of rectal and extremity surface temperatures and whole body metabolic rates failed to show any statistically significant effects that could be attributed to the influence of glycine, as compared to glucose control measurements, throughout a 1-hour cold exposure.

Loco Notion
Barmy BR proposed to tether workers to trackside posts as high-speed trains thundered past at 140mph. Bosses wanted human guinea pigs to stand as close as 6ft 6in to the expresses to test the effect of their slipstream. Rail
union chief Jimmy Knapp branded the idea barmy and suggested BR use Transport Secretary John MacGregor instead.
The workers would have been attached to posts by special harnesses that would allow them to move to the side but not forward. They would have been asked for their reaction after the trains had roared past. The tests would have helped to determine the distances from trains at which staff could work in safety. They would have taken place between York and Darlington.
However the Health and Safety Executive banned the scheme. The tests have been postponed pending further discussions to see how BR could get the information another way.
One disgruntled railwayman described the scheme as harebrained and said he joined BR to drive a flipping engine, not to play flipping bondage games. However a number of civilians have volunteered to take part in the scheme, preferably dressed in leather and chained from head to toe.
The effect when someone stands in the slipstream of a high-speed train is likely to be they'd get sucked under it. If tied to a post perhaps it would suck their boots off, or maybe they'd go blue in the face.
The idea is on a par to that of abolishing the timetable to stop the trains running late.

To test that hypothesis, co-authors Rodger Kram and James Wilson spent the summer of 2020 training until they could haul a heavy log some 15 miles using tumplines. "Some people baked sourdough bread during COVID," said Kram, an emeritus professor of integrative physiology at the University of Colorado at Boulder. "Instead, we carried sand and heavy logs around using our heads."

To investigate these issues, we prospectively studied participants in a jalapeno-pepper eating contest. Subjects included three women and two men ranging in age from 22 to 42. None had a history of lacrimation, rhinorrhea, dysuria or discomfort on defecation before the contest. One was a smoker, and one had cough and scanty sputum production before the contest.

After giving informed consent, subjects consumed as many large jalapenos as could be tolerated in a three-minute period. The number of peppers consumed ranged from three to 13, with a median of five. Three of the participants noted lacrimation and rhinorrhea immediately after the contest. In none did cough or sputum production develop. One male subject complained of dysuria, and four of five noted a burning discomfort on defecation within 24 hours of the contest.

The limited information obtained from this study does not indicate clinical usefulness of jalapeno as an expectorant. We believe that jalapenos may well be the cause of transient dysuria and, in addition, may result in a syndrome of burning defecation that might appropriately be termed "jalaproctitis."