My experience with frozen sections enables me to offer the following directions for making them. First, be very sure that the body, or part, to be frozen is in precisely the position you desire, and that there are no folds or indentations in the skin. I always use natural cold when possible. Weather much about zero (Fahrenheit) is unsatisfactory; but if the part is thoroughly chilled by several days' exposure to a pretty low temperature, a night of 10° may possibly finish it. Salt and ice, or snow, no doubt, will answer the purpose, but much time and patience are required. It is essential that the melted ice should have a chance to run off. The body should be frozen like a rock—so much so that the operator cannot tell whether he is cutting bone or muscle. Tooth is the only tissue he should be able to recognize. The sections should be made in a cold room, with a very sharp saw that has been chilled. When a section is cut, its surface is obscured by a thick half-frozen saw-dust, which is doubly thick if the freezing is not quite sufficient. It is wisest, if time allows, to remove this at once, which is done by pouring a little hot water over the section and brushing or scraping it off rapidly and carefully. This is a very delicate part of the process, and its successful performance has much to do with the beauty of the specimen. If it is to be kept, it should be laid on a piece of glass or wood, and placed at once, while still frozen, in cold alcohol.

In corneal transplant, also known as keratoplasty, a patient's damaged cornea is replaced by the cornea from the eye of a human cadaver. This is the most common type of human transplant surgery and has the highest success rate...
the eye is held open with a speculum. A laser is used to make an initial cut in the existing cornea. The surgeon uses scissors to remove it, and a donor cornea is placed. It is stitched with very fine sutures.

for a variety of reasons it has proven difficult to anaesthetize hippopotamuses. The thick skin and the dense subcutaneous tissue make it difficult to introduce sufficient amounts of anesthetics and opioid-based anesthetics often cause breathing irregularities and occasionally even death. In addition, the level of anesthesia is only rarely sufficient to enable surgery to be undertaken: few vets wish to be around when a drugged hippopotamus starts to wake up.

To the Editor:
I find your piece embarrassing and unworthy of your Internet service.
If you had bothered to do some research, even just reading eMedicine, you would find that curettage, not excision, is the recommended treatment -- a far more sterile version of a fingernail surgery. The curettage procedure is usually nonscarring though rarely some mild hypopigmentation may result.
The use of fingernail surgery is to be condemned as it is a bacterially contaminated area.
Picking at one's own skin with the fingernails is a bad habit and in its extreme form can become obsessive and result in scarring -- a disorder known as neurotic excoriation.
Many elderly gentlemen will pick at solar keratoses on their scalp, leaving it in a persistent state of bleeding and infection; I sincerely hope that you are not headed in this direction.
If your medical colleagues excise your seb warts or cause significant scars, or if you suspect that they choose their therapies on the basis of cost benefit to themselves, I suggest you take the matter up with your State Medical Board rather than indulging in self-injury.
If there is any doubt about the diagnosis, the curetted specimen can be sent for pathology.
Cheers,
Philip Bekhor
Melbourne, Victoria, Australia